王巧玲  /  

—— 硕士生导师 ——

学术学位

—— 硕士生招生专业 ——

妇产科学

—— 研究方向 ——

肠道菌群及小分子代谢物调控女性生殖健康的机制研究

—— 学术任职 ——

2015年10月－2019年10月，比利时荷语鲁汶大学（KU Leuven），生物医学专业，博士学位；
2020年01月－2023年10月，上海交通大学医学院附属瑞金医院，内分泌代谢病研究所，博士后；
2023年11月－至今，同济大学附属妇产科医院，生殖医学中心，助理研究员；同济大学高等研究院副研究员

—— 科研项目 ——

2026-01至2029-12，异戊烯焦磷酸通过抗菌肽β-defensin调控肥胖女性卵泡发育的机制研究，国自然面上项目，49万元，主持；
2023-01 至 2025-12，多形拟杆菌调控肠道抗菌肽α-defensin分泌干预慢性低度炎症的机制研究，国自然青年基金项目，30万元，主持；
2025-05 至 2028-05，未成熟卵母细胞体外培养技术在多囊卵巢综合征患者中的应用研究，院级临床研究青年项目，10万元，主持；
2021-02 至 2022-10，Akkermansia muciniphila调控GLP-1分泌干预肥胖的机制研究，瑞金医院青年基金培育项目，7万元，主持。

—— 学术论文 ——

1. Kathrin I. Liszt*, Qiaoling Wang*, Mona Farhadipour, Anneleen Segers, Theo Thijs, Linda Nys, Ellen Deleus, Bart Van der Schueren, Christopher Gerner, Benjamin Neuditschko, Laurens J. Ceule mans, Matthias Lannoo, Jan Tack, Inge Depoortere^#. Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity. The Journal of Clinical Investigation, 2022, 132(3): e144828. Q1 / IF 19.456
2. Qiaoling Wang*, Huibin Lin, Chongrong Shen, Minchun Zhang, Xingyu Wang, Miaomiao Yuan, Mingyang Yuan, Sheng Jia, Zhiwen Cao, Chao Wu, Banru Chen, Aibo Gao, Yufang Bi, Guang Ning, Weiqing Wang, Jiqiu Wang, Ruixin Liu^＃. Gut microbiota regulates postprandial GLP-1 response via ileal bile acid-TGR5 signaling. Gut Microbes, 2023, 15(2): 2274124. Q1 / IF 12.2
3. Chongrong Shen*, Yanru Chen*, Qiaoling Wang*, Yingkai Sun, Huibin Lin, Mengshan Ni, Yufei Chen, Ling Zhang, Jiabin Jin, Xiayang Ying, Yuyao Zou, Xiaolin Wang, Yaorui Ye, Miaomiao Yuan, Nan Yin, Zhiwen Cao, Yifei Zhang, Weiqiong Gu, Weiqing Wang, Guang Ning, Jiqiu Wang, Shaoqian Zhao^#, Jie Hong^#, Ruixin Liu^#. Fecal short chain fatty acids modify therapeutic effects of sleeve gastrectomy. Frontiers in Endocrinology, 2023: 1277035. Q3/IF 5.2
4. Xingyu Wang*, Zhongle Cai*, Qiaoling Wang*, Chao Wu*, Yingkai Sun, Zhifeng Wang, Xiaoqiang Xu, Wenzhi Xue, Zhiwen Cao, Minchun Zhang, Yinmeng Zhu, Huibin Lin, Yi Zhang, Mingyang Yuan, Yuxiao Zhao, Aibo Gao, Yuqiang Yu, Yufang Bi, Weiqing Wang^#, Jiqiu Wang^#, Guang Ning^#, Ruixin Liu^#. BT MCM mediated-propionate biosynthesis in Bacteroides promotes intestinal goblet cell differentiation and homeostasis. Cell Host & Microbe, 2024, 32: 1-16. Q1 / IF 20.6
5. Huibin Lin*, Qiaoling Wang*, Aibo Gao*, Yingkai Sun, Chongrong Shen, Yufei Chen, Zhifeng Wang, Xiaoqiang Xu, Mengshan Ni, Yanru Chen, Juan Zhang, Yaogan Luo, Xu Lin, Yufang Bi, Guang Ning, Weiqing Wang, Jie Hong, Weiqiong Gu^#, Jiqiu Wang^#, Ruixin Liu^#. Enteropancreatic hormone changes in caloric-restricted diet interventions associate with post-intervention weight maintenance. Clinical Nutrition, 2024, 43: 5-14. Q1/IF 6.6
6. Qiaoling Wang*, Fengli Chi*, Yingdong Liu*, Qiurong Chang, Siyu Chen, Pengcheng Kong, Wanli Yang, Wenqiang Liu, Xiaoming Teng^#, Yan Zhao^#, Yi Guo^#. Polyethylene microplastic exposure adversely affects oocyte quality in human and mouse. Environment International, 2025, 195:109236. Q1/IF 9.7
7. Qiaoling Wang, Jingwen Lang, Yunqing Zhi, Xiuxian Zhu^#, Yonglun Fu^#. Predicting factors of ovarian responses in infertile women with polycystic ovary syndrome undergoing IVF/ICSI. Journal of Assisted Reproduction and Genetics, 2025, 42:865-874. Q3/IF 2.7
8. Junting Xu*, Qiaoling Wang*, Xianting Jiao*, Pengcheng Kong, Siyu Chen, Wanli Yang, Wenqiang Liu, Kunming Li^#, Xiaoming Teng^#, and Yi Guo^#. Association between Perfluorooctanoic Acid–Related Poor Embryo Quality and Metabolite Alterations in Human Follicular Fluid during IVF: A Cohort Study. Environmental Health Perspectives, 2025, 133(6):067017. Q1/IF 9.8
9. Xiuxian Zhu*, Qiaoling Wang*, Jingwen Lang, Yunqing Zhi, Yonglun Fu^# and Shihua Bao^#. Role of follicle-stimulating hormone receptor polymorphism in predicting ovarian response to letrozole in women with polycystic ovary syndrome during ovulation induction. Frontiers in Endocrinology, 2025:1585655. Q3/IF 4.6

        10.Xiuxian Zhu*, Jingwen Lang*, Yunqing Zhi, Qiaoling Wang^#, Yonglun Fu^#. A Novel Letrozole Stair-Step Duration Regimen for                 Ovulation Induction in Women with Polycystic Ovary Syndrome and Letrozole Resistance. Drug Design, Development and Therapy, 2025:19 8793–8803. Q3/IF 5.1