吴丽  /  

—— 硕士生导师 ——

学术型硕导

—— 硕士生招生专业 ——

生物学

—— 研究方向 ——

体细胞重编程与干细胞定向分化、女性生殖系统疾病的体外模拟和干细胞治疗

—— 学术任职 ——

The Journal of Molecular Biology 编委会成员

—— 科研项目 ——

2023年1月至 2026年12月 32270840 METTL14以m6A非依赖方式驱动衰老相关分泌表型促进体细胞重编程的机制研究 国家自然科学基金面上项目

—— 学术论文 ——

1. Chen T#, Xu Y#, Xu X#, Wang J#, Qiu Z, Yu Y, Jiang X, Shao W, Bai D, Wang M, Mei S, Cheng T, Wu L*, Gao S*, Che X*. Comprehensive transcriptional atlas of human adenomyosis deciphered by the integration of single-cell RNA-sequencing and spatial transcriptomics. Protein Cell. 2024 Jul 1;15(7):530-546. 2. Shen J#, Wu L#*, Shi X, Chen G, Liu T, Xu F, Xu X, Kou X, Zhao Y, Wang H, Wang C, Gao S*, Xu S*. Transplantation of the LRP1high subpopulation of human umbilical cord-derived mesenchymal stem cells improves ovarian function in mice with premature ovarian failure and aged mice. Stem Cell Res Ther. 2024 Mar 5;15(1):64. 3. Liu D#, Guan X#, Liu W, Jia Y, Zhou H, Xi C, Zhao M, Fang Y, Wu L*, Li K*. Identification of transcriptome characteristics of granulosa cells and the possible role of UBE2C in the pathogenesis of premature ovarian insufficiency. J Ovarian Res. 2023 Oct 17;16(1):203. 4. Xi C#, Sun J#, Xu X, Wu Y, Kou X, Zhao Y, Shen J, Dong Y, Chen K, Su Z, Liu D, Ye W, Liu Y, Zhang R, Xu Y, Wang H, Hao L*, Wu L*, Gao S*. Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming. Stem Cell Reports. 2022 Aug 9;17(8):1799-1809.