刘文强  /  

—— 博士生导师 ——

学术型博导

—— 博士生招生专业 ——

生物学

—— 硕士生导师 ——

学术型硕导

—— 硕士生招生专业 ——

生物学

—— 研究方向 ——

1．哺乳动物及人早期胚胎发育调控 2．胚胎发育异常的机制及干预 3．不育不孕的遗传学机制及辅助生殖技术

—— 学术任职 ——

1．中国细胞生物学学会生殖细胞生物学分会委员 2．上海市医学会生殖医学分会委员

—— 科研项目 ——

1．科技部, 重点研发计划（青年项目）, 细胞全能性获得的表观调控机制及基于干细胞的类胚胎构建 , 2021-12 至 2026-06, 500万元, 在研, 主持 2．国家自然科学基金委员会, 优秀青年科学基金项目, 表观修饰异常与胚胎发育缺陷, 2021-01-01 至 2023-12-31, 120万元, 结题, 主持 3．国家自然科学基金委员会, 面上项目, 组蛋白甲基转移酶Kmt2e通过H3K4me3修饰影响IVF胚胎植入及胎盘发育的机制研究, 2023-01-01 至 2026-12-31, 54万元, 在研, 主持

—— 学术论文 ——

1．Chenxiang Xi#; Zihui Yan#; Dandan Bai#; Yalin Zhang#; Beiying Wang#; Xiaoxiao Han#; Li Wu; Xiaohui Shi; Zhiyi Hu; Ming Tang; Zhongqu Su; Yingdong Liu; Binya Liu; Jiqing Yin; Hong Wang; Xiaocui Li*; Yanping Zhang*; Shaorong Gao*; Wenqiang Liu*; Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy, Protein & Cell, 2024, 15(6), 460–473. 2．Yanhe Li#; Caihong Zheng#; Yingdong Liu; Jincan He; Qiang Zhang; Yalin Zhang; Xiaochen Kou; Yanhong Zhao; Kuisheng Liu; Dandan Bai; Yanping Jia; Xiaoxiao Han; Yifan Sheng; Jiqing Yin; Hong Wang; Shuai Gao*; Wenqiang Liu*; Shaorong Gao*; Inhibition of Wnt activity improves periimplantation development of somatic cell nuclear transfer embryos, National Science Review, 2023, 10(9): nwad173. 3．Kuisheng Liu#; Xiaocui Xu#; Dandan Bai#; Yanhe Li; Yalin Zhang; Yanping Jia; Mingyue Guo; Xiaoxiao Han; Yingdong Liu; Yifan Sheng; Xiaochen Kou; Yanhong Zhao; Jiqing Yin; Sheng Liu; Jiayu Chen; Hong Wang; Yixuan Wang; Wenqiang Liu*; Shaorong Gao*; Bilineage embryo-like structure from EPS cells can produce live mice with tetraploid trophectoderm, Protein & Cell, 2023, 14(4): 262-278. 4．Hui Yang#; Dandan Bai#; Yanhe Li#; Zhaowei Yu#; Chenfei Wang; Yifan Sheng; Wenqiang Liu*; Shaorong Gao*; Yong Zhang*; Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo, Nature Cell Biology, 2022, 24(5): 783-792. IF 17.3 5．Dandan Ba#i; Jin Sun#; Chuan Chen; Yanping Jia; Yanhe Li; Kuisheng Liu; Yalin Zhang; Jiqing Yin; Yingdong Liu; Xiaoxiao Han; Jingling Ruan; Xiaochen Kou; Yanhong Zhao; Hong Wang; Zheng Wang; Miaoxin Chen; Xiaoming Teng; Cizhong Jiang*; Shaorong Gao*; Wenqiang Liu*; Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos, Cell Reports, 2022, 39(5): 110784.